The intensive care medicine agenda on acute kidney injury.
Identifieur interne : 000201 ( Main/Exploration ); précédent : 000200; suivant : 000202The intensive care medicine agenda on acute kidney injury.
Auteurs : Peter Pickkers [Pays-Bas] ; Marlies Ostermann [Royaume-Uni] ; Michael Joannidis [Autriche] ; Alexander Zarbock [Allemagne] ; Eric Hoste [Belgique] ; Rinaldo Bellomo [Australie] ; John Prowle [Royaume-Uni] ; Michael Darmon [France] ; Joseph V. Bonventre [États-Unis] ; Lui Forni [Royaume-Uni] ; Sean M. Bagshaw [Canada] ; Miet Schetz [Belgique]Source :
- Intensive care medicine [ 1432-1238 ] ; 2017.
Abstract
Acute kidney injury (AKI) is a common complication in the critically ill. Current standard of care mainly relies on identification of patients at risk, haemodynamic optimization, avoidance of nephrotoxicity and the use of renal replacement therapy (RRT) in established AKI. The detection of early biomarkers of renal tissue damage is a recent development that allows amending the late and insensitive diagnosis with current AKI criteria. Increasing evidence suggests that the consequences of an episode of AKI extend long beyond the acute hospitalization. Citrate has been established as the anticoagulant of choice for continuous RRT. Conflicting results have been published on the optimal timing of RRT and on the renoprotective effect of remote ischaemic preconditioning. Recent research has contradicted that acute tubular necrosis is the common pathology in AKI, that septic AKI is due to global kidney hypoperfusion, that aggressive fluid therapy benefits the kidney, that vasopressor therapy harms the kidney and that high doses of RRT improve outcome. Remaining uncertainties include the impact of aetiology and clinical context on pathophysiology, therapy and prognosis, the clinical benefit of biomarker-driven interventions, the optimal mode of RRT to improve short- and long-term patient and kidney outcomes, the contribution of AKI to failure of other organs and the optimal approach for assessing and promoting renal recovery. Based on the established gaps in current knowledge the trials that must have priority in the coming 10 years are proposed together with the definition of appropriate clinical endpoints.
DOI: 10.1007/s00134-017-4687-2
PubMed: 28138736
Affiliations:
- Allemagne, Australie, Autriche, Belgique, Canada, France, Pays-Bas, Royaume-Uni, États-Unis
- Angleterre, District de Münster, Grand Londres, Gueldre, Rhénanie-du-Nord-Westphalie, Victoria (État)
- Londres, Melbourne, Münster, Nimègue
- Université de Londres, Université de Melbourne
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001314
- to stream PubMed, to step Curation: 001292
- to stream PubMed, to step Checkpoint: 001292
- to stream Ncbi, to step Merge: 004238
- to stream Ncbi, to step Curation: 004238
- to stream Ncbi, to step Checkpoint: 004238
- to stream Main, to step Merge: 000196
- to stream Main, to step Curation: 000201
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The intensive care medicine agenda on acute kidney injury.</title><author><name sortKey="Pickkers, Peter" sort="Pickkers, Peter" uniqKey="Pickkers P" first="Peter" last="Pickkers">Peter Pickkers</name><affiliation wicri:level="3"><nlm:affiliation>Department of Intensive Care Medicine (710), Radboud University Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Intensive Care Medicine (710), Radboud University Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Ostermann, Marlies" sort="Ostermann, Marlies" uniqKey="Ostermann M" first="Marlies" last="Ostermann">Marlies Ostermann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Critical Care, Guy's and St Thomas' Hospital, King's College London, London, SE1 9RT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Critical Care, Guy's and St Thomas' Hospital, King's College London, London, SE1 9RT</wicri:regionArea><wicri:noRegion>SE1 9RT</wicri:noRegion></affiliation></author><author><name sortKey="Joannidis, Michael" sort="Joannidis, Michael" uniqKey="Joannidis M" first="Michael" last="Joannidis">Michael Joannidis</name><affiliation wicri:level="1"><nlm:affiliation>Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Zarbock, Alexander" sort="Zarbock, Alexander" uniqKey="Zarbock A" first="Alexander" last="Zarbock">Alexander Zarbock</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesiology, Critical Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, Building A1, 48149, Münster, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Anesthesiology, Critical Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, Building A1, 48149, Münster</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Münster</region><settlement type="city">Münster</settlement></placeName></affiliation></author><author><name sortKey="Hoste, Eric" sort="Hoste, Eric" uniqKey="Hoste E" first="Eric" last="Hoste">Eric Hoste</name><affiliation wicri:level="1"><nlm:affiliation>Department of Intensive Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Intensive Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><affiliation wicri:level="4"><nlm:affiliation>School of Medicine, The University of Melbourne, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine, The University of Melbourne, Melbourne, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Prowle, John" sort="Prowle, John" uniqKey="Prowle J" first="John" last="Prowle">John Prowle</name><affiliation wicri:level="4"><nlm:affiliation>William Harvey Research Institute, Queen Mary University of London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>William Harvey Research Institute, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Darmon, Michael" sort="Darmon, Michael" uniqKey="Darmon M" first="Michael" last="Darmon">Michael Darmon</name><affiliation wicri:level="1"><nlm:affiliation>Medical-Surgical ICU, Saint-Etienne University Hospital and Jacques Lisfranc Medical School, Saint-Etienne, 42000, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Medical-Surgical ICU, Saint-Etienne University Hospital and Jacques Lisfranc Medical School, Saint-Etienne, 42000</wicri:regionArea><wicri:noRegion>42000</wicri:noRegion><wicri:noRegion>42000</wicri:noRegion></affiliation></author><author><name sortKey="Bonventre, Joseph V" sort="Bonventre, Joseph V" uniqKey="Bonventre J" first="Joseph V" last="Bonventre">Joseph V. Bonventre</name><affiliation wicri:level="1"><nlm:affiliation>Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115</wicri:regionArea><wicri:noRegion>02115</wicri:noRegion></affiliation></author><author><name sortKey="Forni, Lui" sort="Forni, Lui" uniqKey="Forni L" first="Lui" last="Forni">Lui Forni</name><affiliation wicri:level="1"><nlm:affiliation>Surrey Perioperative Anaesthesia and Critical Care Collaborative Research Group, Royal Surrey County Hospital, NHS Foundation Trust and School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Surrey Perioperative Anaesthesia and Critical Care Collaborative Research Group, Royal Surrey County Hospital, NHS Foundation Trust and School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH</wicri:regionArea><wicri:noRegion>GU2 7XH</wicri:noRegion></affiliation></author><author><name sortKey="Bagshaw, Sean M" sort="Bagshaw, Sean M" uniqKey="Bagshaw S" first="Sean M" last="Bagshaw">Sean M. Bagshaw</name><affiliation wicri:level="1"><nlm:affiliation>Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 2-124 Clinical Sciences Building, 8440-112 ST NW, Edmonton, AB, T6G2B7, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 2-124 Clinical Sciences Building, 8440-112 ST NW, Edmonton, AB, T6G2B7</wicri:regionArea><wicri:noRegion>T6G2B7</wicri:noRegion></affiliation></author><author><name sortKey="Schetz, Miet" sort="Schetz, Miet" uniqKey="Schetz M" first="Miet" last="Schetz">Miet Schetz</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Department and Laboratory of Intensive Care Medicine, Division of Cellular and Molecular Medicine, KU Leuven University, Herestraat 49, B3000, Louvain, Belgium. marie.schetz@uzleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Department and Laboratory of Intensive Care Medicine, Division of Cellular and Molecular Medicine, KU Leuven University, Herestraat 49, B3000, Louvain</wicri:regionArea><wicri:noRegion>Louvain</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28138736</idno><idno type="pmid">28138736</idno><idno type="doi">10.1007/s00134-017-4687-2</idno><idno type="wicri:Area/PubMed/Corpus">001314</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001314</idno><idno type="wicri:Area/PubMed/Curation">001292</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001292</idno><idno type="wicri:Area/PubMed/Checkpoint">001292</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001292</idno><idno type="wicri:Area/Ncbi/Merge">004238</idno><idno type="wicri:Area/Ncbi/Curation">004238</idno><idno type="wicri:Area/Ncbi/Checkpoint">004238</idno><idno type="wicri:Area/Main/Merge">000196</idno><idno type="wicri:Area/Main/Curation">000201</idno><idno type="wicri:Area/Main/Exploration">000201</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The intensive care medicine agenda on acute kidney injury.</title><author><name sortKey="Pickkers, Peter" sort="Pickkers, Peter" uniqKey="Pickkers P" first="Peter" last="Pickkers">Peter Pickkers</name><affiliation wicri:level="3"><nlm:affiliation>Department of Intensive Care Medicine (710), Radboud University Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Intensive Care Medicine (710), Radboud University Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Ostermann, Marlies" sort="Ostermann, Marlies" uniqKey="Ostermann M" first="Marlies" last="Ostermann">Marlies Ostermann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Critical Care, Guy's and St Thomas' Hospital, King's College London, London, SE1 9RT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Critical Care, Guy's and St Thomas' Hospital, King's College London, London, SE1 9RT</wicri:regionArea><wicri:noRegion>SE1 9RT</wicri:noRegion></affiliation></author><author><name sortKey="Joannidis, Michael" sort="Joannidis, Michael" uniqKey="Joannidis M" first="Michael" last="Joannidis">Michael Joannidis</name><affiliation wicri:level="1"><nlm:affiliation>Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Zarbock, Alexander" sort="Zarbock, Alexander" uniqKey="Zarbock A" first="Alexander" last="Zarbock">Alexander Zarbock</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesiology, Critical Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, Building A1, 48149, Münster, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Anesthesiology, Critical Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, Building A1, 48149, Münster</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Münster</region><settlement type="city">Münster</settlement></placeName></affiliation></author><author><name sortKey="Hoste, Eric" sort="Hoste, Eric" uniqKey="Hoste E" first="Eric" last="Hoste">Eric Hoste</name><affiliation wicri:level="1"><nlm:affiliation>Department of Intensive Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Intensive Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><affiliation wicri:level="4"><nlm:affiliation>School of Medicine, The University of Melbourne, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine, The University of Melbourne, Melbourne, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Prowle, John" sort="Prowle, John" uniqKey="Prowle J" first="John" last="Prowle">John Prowle</name><affiliation wicri:level="4"><nlm:affiliation>William Harvey Research Institute, Queen Mary University of London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>William Harvey Research Institute, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Darmon, Michael" sort="Darmon, Michael" uniqKey="Darmon M" first="Michael" last="Darmon">Michael Darmon</name><affiliation wicri:level="1"><nlm:affiliation>Medical-Surgical ICU, Saint-Etienne University Hospital and Jacques Lisfranc Medical School, Saint-Etienne, 42000, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Medical-Surgical ICU, Saint-Etienne University Hospital and Jacques Lisfranc Medical School, Saint-Etienne, 42000</wicri:regionArea><wicri:noRegion>42000</wicri:noRegion><wicri:noRegion>42000</wicri:noRegion></affiliation></author><author><name sortKey="Bonventre, Joseph V" sort="Bonventre, Joseph V" uniqKey="Bonventre J" first="Joseph V" last="Bonventre">Joseph V. Bonventre</name><affiliation wicri:level="1"><nlm:affiliation>Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115</wicri:regionArea><wicri:noRegion>02115</wicri:noRegion></affiliation></author><author><name sortKey="Forni, Lui" sort="Forni, Lui" uniqKey="Forni L" first="Lui" last="Forni">Lui Forni</name><affiliation wicri:level="1"><nlm:affiliation>Surrey Perioperative Anaesthesia and Critical Care Collaborative Research Group, Royal Surrey County Hospital, NHS Foundation Trust and School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Surrey Perioperative Anaesthesia and Critical Care Collaborative Research Group, Royal Surrey County Hospital, NHS Foundation Trust and School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH</wicri:regionArea><wicri:noRegion>GU2 7XH</wicri:noRegion></affiliation></author><author><name sortKey="Bagshaw, Sean M" sort="Bagshaw, Sean M" uniqKey="Bagshaw S" first="Sean M" last="Bagshaw">Sean M. Bagshaw</name><affiliation wicri:level="1"><nlm:affiliation>Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 2-124 Clinical Sciences Building, 8440-112 ST NW, Edmonton, AB, T6G2B7, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 2-124 Clinical Sciences Building, 8440-112 ST NW, Edmonton, AB, T6G2B7</wicri:regionArea><wicri:noRegion>T6G2B7</wicri:noRegion></affiliation></author><author><name sortKey="Schetz, Miet" sort="Schetz, Miet" uniqKey="Schetz M" first="Miet" last="Schetz">Miet Schetz</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Department and Laboratory of Intensive Care Medicine, Division of Cellular and Molecular Medicine, KU Leuven University, Herestraat 49, B3000, Louvain, Belgium. marie.schetz@uzleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Department and Laboratory of Intensive Care Medicine, Division of Cellular and Molecular Medicine, KU Leuven University, Herestraat 49, B3000, Louvain</wicri:regionArea><wicri:noRegion>Louvain</wicri:noRegion></affiliation></author></analytic><series><title level="j">Intensive care medicine</title><idno type="eISSN">1432-1238</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Acute kidney injury (AKI) is a common complication in the critically ill. Current standard of care mainly relies on identification of patients at risk, haemodynamic optimization, avoidance of nephrotoxicity and the use of renal replacement therapy (RRT) in established AKI. The detection of early biomarkers of renal tissue damage is a recent development that allows amending the late and insensitive diagnosis with current AKI criteria. Increasing evidence suggests that the consequences of an episode of AKI extend long beyond the acute hospitalization. Citrate has been established as the anticoagulant of choice for continuous RRT. Conflicting results have been published on the optimal timing of RRT and on the renoprotective effect of remote ischaemic preconditioning. Recent research has contradicted that acute tubular necrosis is the common pathology in AKI, that septic AKI is due to global kidney hypoperfusion, that aggressive fluid therapy benefits the kidney, that vasopressor therapy harms the kidney and that high doses of RRT improve outcome. Remaining uncertainties include the impact of aetiology and clinical context on pathophysiology, therapy and prognosis, the clinical benefit of biomarker-driven interventions, the optimal mode of RRT to improve short- and long-term patient and kidney outcomes, the contribution of AKI to failure of other organs and the optimal approach for assessing and promoting renal recovery. Based on the established gaps in current knowledge the trials that must have priority in the coming 10 years are proposed together with the definition of appropriate clinical endpoints.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>France</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Angleterre</li><li>District de Münster</li><li>Grand Londres</li><li>Gueldre</li><li>Rhénanie-du-Nord-Westphalie</li><li>Victoria (État)</li></region><settlement><li>Londres</li><li>Melbourne</li><li>Münster</li><li>Nimègue</li></settlement><orgName><li>Université de Londres</li><li>Université de Melbourne</li></orgName></list><tree><country name="Pays-Bas"><region name="Gueldre"><name sortKey="Pickkers, Peter" sort="Pickkers, Peter" uniqKey="Pickkers P" first="Peter" last="Pickkers">Peter Pickkers</name></region></country><country name="Royaume-Uni"><noRegion><name sortKey="Ostermann, Marlies" sort="Ostermann, Marlies" uniqKey="Ostermann M" first="Marlies" last="Ostermann">Marlies Ostermann</name></noRegion><name sortKey="Forni, Lui" sort="Forni, Lui" uniqKey="Forni L" first="Lui" last="Forni">Lui Forni</name><name sortKey="Prowle, John" sort="Prowle, John" uniqKey="Prowle J" first="John" last="Prowle">John Prowle</name></country><country name="Autriche"><noRegion><name sortKey="Joannidis, Michael" sort="Joannidis, Michael" uniqKey="Joannidis M" first="Michael" last="Joannidis">Michael Joannidis</name></noRegion></country><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Zarbock, Alexander" sort="Zarbock, Alexander" uniqKey="Zarbock A" first="Alexander" last="Zarbock">Alexander Zarbock</name></region></country><country name="Belgique"><noRegion><name sortKey="Hoste, Eric" sort="Hoste, Eric" uniqKey="Hoste E" first="Eric" last="Hoste">Eric Hoste</name></noRegion><name sortKey="Schetz, Miet" sort="Schetz, Miet" uniqKey="Schetz M" first="Miet" last="Schetz">Miet Schetz</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name></region></country><country name="France"><noRegion><name sortKey="Darmon, Michael" sort="Darmon, Michael" uniqKey="Darmon M" first="Michael" last="Darmon">Michael Darmon</name></noRegion></country><country name="États-Unis"><noRegion><name sortKey="Bonventre, Joseph V" sort="Bonventre, Joseph V" uniqKey="Bonventre J" first="Joseph V" last="Bonventre">Joseph V. Bonventre</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Bagshaw, Sean M" sort="Bagshaw, Sean M" uniqKey="Bagshaw S" first="Sean M" last="Bagshaw">Sean M. Bagshaw</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000201 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000201 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28138736
|texte= The intensive care medicine agenda on acute kidney injury.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28138736" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |